Human chorionic gonadotrophin: Comparative studies of ovarian uptake in mammals
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چکیده
منابع مشابه
Human chorionic gonadotrophin: comparative studies of ovarian uptake in mammals.
-l. The localization of radiolabeled human chorionic gonadotrophin (~2SI-HCG) was studied in a number of commonly used mammalian animal models. 2. The ovary proved to be the target organ for ~25I-HCG in all animals studied. 3. The optimum time for the localization of HCG in the ovary varied in all the mammals extending from 1.5 to 4 hr. 4. HCG is apparently used in the target cell for only a br...
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Studies in both patients and mice have been carried out using heterologous antibody directed at secreted products of tumors. In preliminary therapeutic studies in patients with drug-resistant choriocarcinoma and malignant teratoma, heterologous anti-human chorionic gonadotrophin (HCG) and anti-alpha-fetoprotein have been combined with continued cytotoxic chemotherapy. The results to date, altho...
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Background : Gestational trophoblastic neoplasia (GTN) disease is excessive and inappropriate proliferation of trophoblast after termination of the pregnancy. Many attempts have been made to improve follow-up procedures, but no studies have evaluated Human Chorionic Gonadotrophin (HCG) as a post treatment indicator. Thus we aimed to know β-HCG variability in post treatment pregnancies. Meth...
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Serum human chorionic gonadotrophin (HCG) concentrations were determined by radioimmunoassay with an antiserum specific to HCG beta-subunit in 42 patients with hyperemesis gravidarum and 115 women with normal pregnancies. Mean concentrations (+/- SE of mean) were higher in the women with hyperemesis gravidarum at 7-8 weeks (40.8 +/- 5.2 IU/ml v 22.1 +/- 1.4 IU/ml; P less than 0.001), 9-11 weeks...
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ژورنال
عنوان ژورنال: Comparative Biochemistry and Physiology Part A: Physiology
سال: 1975
ISSN: 0300-9629
DOI: 10.1016/s0300-9629(75)80121-6